Mega Sena is Brazil's largest and most popular lottery game, offering players the chance to win substantial jackpots with draws held twice a week on Wednesdays and Saturdays. Established in 1996, Mega Sena has become a favorite among Brazilians for its simple format and impressive prize potential. To play Mega Sena, participants select six numbers from a pool of 60. Matching all six numbers wins the jackpot.